Effects of caffeine supplementation on lipid profile and handgrip strength in cirrhotic patients: a randomized, placebo- controlled, clinical trial
December 4, 2025
Conclusion Statement
It can be concluded that supplementation with 400 mg caffeine daily for 8 weeks in patients with cirrhosis may result in improvement of handgrip strength with no significant effect on lipid profile. Further studies with different caffeine dosages, and study duration are needed to find the optimum dosage of supplementation.
Citations
Abbas-Hashemi SA, Yari Z, Hatami B, Anushiravani A, Kolahdoozan S, Zamanian A, Akbarzadeh N, Hekmatdoost A. Effects of caffeine supplementation on lipid profile and handgrip strength in cirrhotic patients: a randomized, placebo- controlled, clinical trial. BMC Nutr. 2025 Dec 4;12(1):6. doi: 10.1186/s40795-025-01217-9. PMID: 41345894; PMCID: PMC12797547.
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